Based on our current laboratory instrumentation, we have the ability to perform the following measurements. Other capabilities exist with our consortium members. Please contact us for specific details.

• Diffusion Coefficient Measurement
  

  	Isotropic		Anisotropic
  Nuclei	H-1, C-13, P-31, N-14	H-1	H-1
  D	10-4 to 10-8 cm2/s	10-4 to 10-6 cm2/s	10-4 to 10-8 cm2/s
  Sample Size	5 mm	70 cm	5 mm
  Temperature	-50 to 200 oC	RT	-50 to 200 oC

• Imaging
  

  Field Strength (Bo)	50 mT	1.5 T	3 T	7 T	11.7 T
  Field of VIew (FOV)	7 cm	4 - 40 cm	4 - 40 cm	4.5 mm	4.5 mm
  Nuclei*	H	H	H	H	H
  Pixel Size	120 μ	80 μ	80 μ	20 μ	20 μ
  Sequences	SE	SE, Grad. Echo, FSE, IR, MRA, D, EPI	SE, Grad. Echo, FSE, IR, MRA, D, EPI	GE, SE, IR	GE, IR

  * Other nuclei available on request.

• MRI and NMR Radio Frequency Coil Tuning
  Tune NMR imaging or spectroscopy coil.
  Frequency Range: 5 to 500 MHz
  Impedance: 50 or 75 Ohms

• MRI and NMR Radio Frequency Coil Construction
  Design and build a radio frequency RF coil for NMR imaging or spectroscopy in the 5 to 500 MHz range.

• High Resolution NMR Spectroscopy
  

  Field Strength (Bo)	7 T (300 MHz)	11.7 T (500 MHz)
  Sample Size	5 mm	5 mm
  Nuclei*	H-1, C-13, P-31, N-15	H-1, C-13, P-31, N-15
  Temperature	-50 to 200 oC	-150 to 150 oC
  1D and 2D Pulse Sequences	Bruker Library	Bruker Library
  Phase	Liquid	Liquid

  * Others are available depending on sensitivity.

• Radio Frequency Magnetic Field Mapping
  Map the transmit and receive radio frequency magnetic field distribution in an MRI coil.
  Spatial resolution = 0.004 of largest coil dimension
  Field resolution = 0.01 of largest field value

• Spin-Lattice Relaxation Time (T1) Measurement
  Analysis: monoexponential, biexponential, multiexponential, and principal component
  

  Field Strength (Bo)	50 μT	1-18 mT*	0.75 T	1.5 T	7 T	11.7 T
  Maximum*	5 s	5 s	10 s	3 s	10 s	10 s
  Minimum*	50 ms	50 ms	10 ms	100 ms	10 ms	10 ms
  Nuclei	H	H	H	H	H + others	H + others
  Temperature	RT	RT	RT	5 to 50 oC	-50 to 200 oC	-150 to 150 oC
  Analysis	ROI	ROI	ROI	ROI & Image	ROI	ROI

  * - Signal strength dependent
  ROI - Region of Interest

• Spin-Spin Relaxation Time (T2) Measurement
  Analysis: monoexponential, biexponential, multiexponential, and principal component
  

  Field Strength (Bo)	50 μT	0.75 T	1.5 T	7 T	11.7 T
  Maximum*	1 s	1 s	1 s	1 s	1 s
  Minimum*	35 ms	1 ms	10 ms	1 ms	1 ms
  Nuclei	H	H	H	H + others	H + others
  Temperature	RT	RT	5 to 50 oC	-50 to 200 oC	-150 to 150 oC
  Analysis	ROI	ROI	ROI & Image	ROI	ROI

  * - Signal strength dependent
  ROI - Region of Interest

• Dielectric Constant & Resistivity
  Measure the relative dielectric constant and resistivity of liquids and gells.
  Frequency Range = 100 kHz - 200 MHz
  Minimum Sample Volume = 5 ml

• MRI Phantom Design and Prototyping
  We specialize in custom engineered phantoms to meet specific QC imaging needs.
  Some examples of our work include:

  Phantom	Features
  Relaxation Time	Fixed T1 and T2 values.
  Resolution	Measure resolution and PSF in 3D without repositioning.
  Diffusion	Water based, selectable D values between DWater and 0.25 DWater.
  fMRI	Switchable T2 value.
  Fat Sat	Variable fat-to-water ratio solution for fat-saturation imaging.
  Digital	Determine segmentation accuracy.