When using a 90-FID pulse sequence and a sample containing all the tissues in question number two, what TR value would
guarantee at least 98% of the signal from all the tissues?
S(TR) = kr(1-e-TR/T1)
where:
TR = repetition time
S(TR) = signal at time TR
r = spin density
k = proportionality constant
T1 = spin-spin relaxation time
Taking the ratio of the observed signal (S(TR) from above) to the signal
at infinitely long TR, gives:
S(TR) / S(TR=inf) = kr(1-e-TR/T1)
/ kr(1-e-inf/T1)
S(TR) / S(TR=inf) = kr(1-e-TR/T1)
/ kr(1)
Setting S(TR) / S(TR=inf.) = 0.98 we have
0.98 = 1-e-TR/T1
ln( 1 - 0.98) = -TR/T1
TR = -T1 * ln( 0.02 )
Using the longest T1 (20 s) to determine TR would ensure 98% signal or better for all of the listed tissues.
TR = -20 s * ln( 0.02 ) = 78.24 s